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Interesting information.  I have prior history of C-diff and concerned if I get pouchitis for this very reason.  I am planning to have dental work done soon and my oral surgeon is looking into what antibiotic I can have and not risk a recurrence of C-diff before he will even begin the process.  I also have allergies to a few antibiotics as well.  Will see how it works out.

Not exactly. While it is generally considered topical, with long term use there can be enough systemic absorption to become an issue. It is inaccurate to say it only is absorbed in the intestine. What is accurate is that it is poorly absorbed.

Biologics are considered a safer long term option than any steroid.

Jan

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