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does this statement make sense or hold water because my digestive symptoms started immediately after my vasectomy then a few years later was diagnosed with ulcerative colitis?

Vasectomy complications:

Ruptures

Actually, the technical term for this phenomena is a “blowout.” According to Campbell’s Urology (a textbook for urology students and doctors) “The brunt of pressure-induced damage after vasectomy falls on the epididymis and efferent ductules…. It is likely that, in time, all vasectomized men develop ‘blowouts’ in either the epididymis or efferent ducts.” This rupturing can occur spontaneously at any time following vasectomy.

Autoimmune Responses

But that’s not all. When the rupturing occurs, sperm cells enter the blood stream, where they were not naturally intended to be. As a matter of fact, nature makes a very specific point of keeping sperm cells out of the blood stream, because sperm cells have very strong enzymes on their surfaces and only half a DNA strand. What does the body think is happening? The immune system is sent on full alert to fight off a perceived infection of millions of invading cells per day, and the body becomes “autoimmune”, i.e. the body goes to war on itself. Again from Campbell’s Urology: “Vasectomy results in violation of the blood-testis barrier producing detectable levels of serum antisperm antibodies in 60 to 80 per cent of men….” Once this reaction starts, it is nearly impossible to stop, even with a vasectomy reversal. Research has shown that a sperm count taken prior to vasectomy is a good indicator of the likelihood of this autoimmune response; the higher the sperm count, the more likely a man will become autoimmune. Most doctors choose not to do this test prior to vasectomy, or to even inform their patients of the likelihood of this response. What can’t be predicted, however, is the specific reactions a man might have to the formation of these antibodies. That is left purely to chance.

Why is this autoimmune response important? Well, numerous reactions have been identified as part of this autoimmune response. In three men out of five or more, chronic inflammation leads to the formation of a sperm granuloma at the rupture site, which may need to be removed surgically to alleviate painful symptoms. Other types of cysts often form in the epididymis and/or the scrotum including spermatoceles and hydroceles, which may also require further treatment or lead to other problems. The autoimmune response that follows vasectomy has also been linked to an increase in the incidence of numerous diseases by dozens of studies. These diseases include testicular dysfunction and hormonal imbalances, recurrent infections, various forms of cancer, and other immune system deficiencies. According to Dr. H. J. Roberts, an internist who has studied the effects of vasectomy on the immune system for over 30 years, “ no other operation performed on humans even approaches the degree and duration of the multiple immunologic responses that occur in the post-vasectomy state.” The appearance of symptoms to these reactions may take years to manifest.
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Doubt it. The autoimmune response noted is in regard to anti-sperm antibodies, but not necessarily a systemic response.

However, if this was particularly traumatic or there was a related infection, that might be a trigger for a first UC flare.

That said, anything is possible, so I would not rule it out. Still, does it really matter?

Jan Smiler
Sure. There are a great many triggers for UC. Infection seems to be a common one. But extreme stress has been noted to be a trigger to. I don't mean the "my mother-in-law really stresses me out" type of stress, but the type of stress associated with surgery and trauma that causes prolonged secretion of stress hormones. Extreme pain is one of those. You can play "what-if," but realistically, you were likely to encounter some triggering event somewhere along the line.

Jan Smiler

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