Uceris (Budesonide) Rectal for J Pouch Pouchitis/inflammation?

I just requested this from my GI and he told me he could not prescribe it I have many issues at the anastomoses and think this may help with my lower pouch ulcers too. What gives?

I did not do well with enemas. I did take some kind of cortisone foam enema. Had trouble holding it and was ineffective.

Entocort capsules helped me a lot, but you can't stay on them very long. I was very narrowed at the J Pouch inlet with inflammation above the pouch and the entocort helped bring that down. They don't think I have Crohn's, because the inflammation above the pouch is due to feces pooling above the J Pouch inlet due to the narrowing. The pooling of the feces above the pouch has created "fecal stasis" and bacterial overgrowth.

Give the new enemas a try and let us know how they work. And thanks for the info- I may give them a try too as I am better now than when I used the cortisone enemas I could not hold.

I have the exact issue you do Ctbarrister but at the outlet. The narrowed anastomoses causes fecal stasis and pooling in the distal pouch and at the outlet, hence pouchitis from bacterial overgrowth. I think the foam may help me as at times I cannot retain Canasa for a long enough period. I also have inflammation and some ulceration below the anastomoses due to lack of blood flow to this area from the narrowed anastomoses. Not sure meds can really help this issue but I'm always open to trying something new.

Jeane,

They would probably help you more than me if the issue is at the J Pouch outlet. Good luck with it, if you try it.

Thanks. I emailed our GI to ask when we can get a script. Internet says. It until Jan 2015.

Jeane,

Ironically I also sent an email to our mutual GI, just asking him if he thinks Uceris foam is a feasible treatment for the J Pouch, and providing a link to the article about FDA approval which the OP posted above.