UC again after 27 years with pouch ?

Eitan, I'm not quite sure what you (or your doctor) mean by "colitis." If the inflammation is in the small bit of remaining colon (the rectal cuff) we tend to call it "cuffitis." However, a J-pouch can look more and more like colonic tissue over time, and pathologists sometimes interpret it as colon. Some people do get both pouchitis and cuffitis. It sounds like you're getting good results from antibiotics. Do you have a problem, or are you just asking why your "colitis" is responding to antibiotics?

Scott hello

Thanks a lot. The doctor think in two different directions:

1. That the surgeon kept part of the rectum (more than a cuff).

2. That J-pouch look like colonic tissue.

The problem is that I need to take antibiotics for long periods (One month to 3 months) every few months. The GI doesn't like that some of the biopsies showed puchitis and some of them colitis.

Eitan

Eitan, this doesn't need to be so complicated. Cuffitis isn't usually that hard to diagnose, though it can be difficult to treat. Next time your GI takes biopsies he needs to try to keep better track of where they come from, so rectal cuff biopsies don't get mixed up with pouch biopsies (though it can be hard to see the anastamosis after 27 years). If these pathology reports are either saying "colitis" or "pouchitis" (but not both in the same report), then I think the different pathologists may just be interpreting the slides differently, even though they actually look the same every time.