Simponi injections for pouchitis

TinatMember

Hi, I just started self-injections of Simponi, similar to Humira and Remicade, but they happen every 4 weeks and I just wanted to know if anyone else has gone through or currently trying this treatment? If so, how did it or is it going? I've tried Remicade a few years ago, but at the 3rd session had an allergic reaction to it and now I'm hoping the Simponi will be different, as I understand it's a different kind of protein from Remicade.

Thanks,
Tina

1/19/1412:04 AM

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Jan DollarModerator, RN, retired

I've been on Simponi for several years, for arthritis, not pouchitis. However, my pouch has never looked better and I have fewer instances of pouchitis and cuffitis since being on it. No allergies yet. Like Himira, it is a fully humanized protein. Remicade is mouse protein.

Jan

1/19/141:36 AM

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TinatMember

Hi Jan, that is so good to hear, do you remember how long it took effect? And do you still need to take any antibiotics with it? It's been a few days now and I'm not noticing any real difference and am still taking antibiotics with it.

1/19/148:51 PM

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Jan DollarModerator, RN, retired

It can take up to 3 months for full effect. For me, it was about 4-6 weeks before i noticed it.

Jan

1/19/149:09 PM

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