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Years before having my colon removed I got c.diff from taking Cipro for sinus infections.  I wish I  could have taken it for my pouchitis.

I took a lot of flagyl for pouchitis until I it was making my peripheral neuropathy, in my feet, worse. 

I was alternating augmenten and xifaxan before I had surgery diverting to a permanent ileostomy. The latter is very expensive but is specific for intestines. (There's a TV commercial out marketing it for IBS with diarrhea. It includes a pink cartoon glob of intestines.)

I'm not suggesting people don't take these. Just a warning. I had c.diff in my pouch. Many courses of flagyl eventually got rid of it. 

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