I uses to find probiotics really helpful (rice Bio-K usually. but even a nice kombucha would make a difference), but then i got pregnant and suddenly they made me feel like i was being poisoned. I could not stand the thought of them. So I stopped, and still when I try bio-k it makes me feel awful. but Better booch kombucha makes me feel pretty good. But it has a lot of sugar. I have ZERO idea if any of this is helpful! Just to say it all seems to be in flux. Sometimes they are helpful, sometimes not. I used to take them when I was on anti-biotics for pouchitis (cipro and Flagyl. I now refuse to take flagyl it makes me feel so awful I want to tear my skin off!). But now I don't! i have no idea!!!