I started taking them on the advice of my GP who was also a naturopath...I had terrible pouch pain, infections, low resistance and exhaustion...they were pharmaceutical grade and send special order in a refrigerated container.
It took a 30 day supply for me to start to feel normal...then I noticed that my pouch was behaving better and I was less 'runny' and crampy...since then I have been taking 1-2 month runs of them on a 'as needed' basis.
They seem to work for me...hubby takes them when he is feeling bloaty and gassy...Works for him to and he doesn't have a pouch.
It is one of those meds that are not dangerous, could only help and well as the old joke goes...it couldn't hurt!
Sharon
ps...not all probiotics are created equally...make sure that you take a good quality product.