Nighttime fecal incontinence

I have had that off and on, and for me it is Pouchitis. From reading other posts - that could be the culprit. Have you been on Cipro and or Flagyl?

I agree with Doug - this is often a sign of pouchitis. Occasional nighttime “events” may not mean much, but 6 weeks isn’t occasional. If neither Cipro nor Flagyl have worked individually you could try them in combination. That’s what currently works for me.

One intervention that helps some folks is a small fatty “meal” at bedtime, like a spoonful of peanut butter. This won’t fix pouchitis, though.

Yes. I failed to add that I’ve tried a combination of cipro, flagyl with lomotil and Imodium. All those together made no difference. I suspect pouchitis as well, but not sure since multiple days on those antibiotics made no difference.