^^ a generation ago they didn't have UC, or at least nowhere near the volumes of people affected today. A lot of illness can be medically attributed to environmental factors, I honestly believe that the rapid explosion of autoimmune diseases is linked to this too.
Any medication for UC is simply to control the bodies reaction to the environment, we need to be looking outside the body for fixes, i.e. at the area of environmental triggers, pesticides on crops, bulk farming methods, food transportation, storage methods, posture, exercise, water quality etc
That said we are also living longer, which means more chance for organs to wear out, I guess the digestive tract is in constant use, and we are eating foods that differ to our natural (evolved) diet, so that is going to take significant wear and tear.