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OK everyone I have had my jpouch since 1991. 2 years ago I started having severe joint pain and was finally diagnosed with alkolosing spondylitis. I was on humira, Enbrel, and just completed my 5th round of IV remicaid. My blood work was always normal even after the remicaid infusions. I just had blood work and my lfts are very high. I just had a sono and the Dr. called to say I have a diffuse fatty liver and some kind of adenoma in my gall bladder. I have had no pain only joint pain. I am freaking out now I have an app Confused t with a GI tomorrow. Do you think I have that PSC? Anyone??
Sharon

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I had elevated LFTs too, but it was prior to my use of biologics. I had an MRCP (non invasive liver imaging) which did rule out PSC. Fatty liver disease is associated with UC, so try not to jump to conclusions prematurely. Yes, PSC is also associated with UC, but please wait for further testing before you think the worst. My LFTs only improved after my spondylitis diagnosis and starting biologics.

It is possible that in your case, this could be a side effect of your biologic use, and you may need to stop it (a known side effect, and that is why you have the regular bloodwork).

Jan Smiler
Jan Dollar
Mewow posted:
OK everyone I have had my jpouch since 1991. 2 years ago I started having severe joint pain and was finally diagnosed with alkolosing spondylitis. I was on humira, Enbrel, and just completed my 5th round of IV remicaid. My blood work was always normal even after the remicaid infusions. I just had blood work and my lfts are very high. I just had a sono and the Dr. called to say I have a diffuse fatty liver and some kind of adenoma in my gall bladder. I have had no pain only joint pain. I am freaking out now I have an app Confused t with a GI tomorrow. Do you think I have that PSC? Anyone??
Sharon

So what was the diagnosis on this??

Pouchomarx

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