Maybe soothing warm water from both sides of the tube? Warm water enema on one side and some soothing tea (like lemon balm or chamomile or a mix) to drink? Laxatives can be pretty intense. It's hard to know what your body is asking for from out here. What do the doctors say? Do you have an acupuncturist or any other experienced holistic practitioner to help you with this? Someone who can look at your specific conditions and help determine what your body needs?