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Mine was normal, except for one elevated inflammatory marker (CRP for me was up, but ESR was normal). I was negative for rheumatoid factor (only positive in rheumatoid arthritis), ANA (to rule out lupus), and a few other tests.

The arthritis associated with IBD (ankylosing spondylitis and related diseases) is what is called seronegative, meaning the blood tests are negative. Most people with AS are HLA-B27 positive, but the type that is associated with IBD has a lower association, 30-50%. So, there is no diagnostic blood test. They are mostly to rule out other diseases.

That does not mean that you cannot get these other types of arthritis just because you have UC, but if you do, they are independent of the UC and not associated with it.

Jan Smiler
Jan Dollar
Not necessarily. Having UC increases your risk. If you have been on prednisone and recently tapered off of it, you can get a lot of joint pain afterwards. But, it should resolve unless the prednisone was masking an underlying arthritic condition. Of course, long term steroid use can cause arthritic problems, some serious, but they usually affect specific weight bearing joints, not all over pain.

Jan Smiler
Jan Dollar
I quit steroids about five months ago.
But was taking them for years...five years if not more when I had UC.
I also wondered if it was due to using pain meds.
I didn't take any pain meds all night.
But once I get moving around the pain diminishes. ..not competely but almost.
Sometimes I just have to get up in the middle of the night for an hour or so
just to get rid of the pain and go back to bed. But then it just comes back when I
get up in the morning.
I am not a dr of course but can withdrawals from pain meds kick in overnight?
Mysticobra

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