> FINAL DIAGNOSIS
>
> 1. Duodenum, biopsy (A) - Patchy active duodenitis.
> -Negative for granulomas or dysplasia.
>
> 2. Gastric, biopsy (B) - Gastric body-type mucosa without diagnostic
> alteration.
> -Helicobacter pylori organisms not identified.
>
> 3. Esophagus, biopsy (C) - Squamous esophageal mucosa with out diagnostic
> alteration.
> -Negative for eosinophilic esophagitis.
>
> 4. Terminal ileum, biopsy (D) - Patchy chronic active ileitis with focal
> erosion.
> -Negative for granulomas, pyloric gland metaplasia or dysplasia.
>
> 5. Pouch, biopsy (E) - Patchy chronic inactive inflammation.
> -Negative for granulomas, pyloric gland metaplasia or dysplasia.
>
> 6. Rectal cuff, biopsy (F) - Chronic colitis with minimal activity.
> -Negative for granulomas, pyloric gland metaplasia or dysplasia.
>
> LMY/sld 3/20/2013
>
> COMMENT
> A, D. Immunohistochemical staining for IgG4 is pending and the results will
> be reported as an addendum.
>
>
>
>
> Lisa M. Yerian, M.D.
> (Electronic Signature)
> ___________________________________________________________________
>
> SPECIMEN SUBMITTED
> A: DUODENUM, BIOPSY
> B: GASTRIC, BIOPSY
> C: ESOPHAGUS, BIOPSY
> D: TERMINAL ILEUM, BIOPSY
> E: POUCH, BIOPSY
> F: RECTAL CUFF, BIOPSY
>
> ADDENDUM
> Date Ordered: 3/21/2013 Date Reported: 3/21/2013
>
> IgG4 immunostaining performed on specimens A and D is negative.
>
> ANALYTE SPECIFIC REAGENT (ASR) DISCLAIMER
>
> This test was developed and its performance characteristics determined by
> Cleveland Clinic's Robert J. Tomsich Pathology & Laboratory Medicine
> Institute. The U.S. Food and Drug Administration has not approved or
> cleared this test; however, FDA clearance or approval is not currently
> required for clinical use.
>
> LMY/kr 3/21/2013
>
>
> Addendum Pathologist: Lisa M. Yerian, M.D.
> ***Electronic Signature***
>
>
>
>
> CLINICAL DATA
> h/o Crohn's, n/a
> A: R/O CROHN'S, IGG4, AUTOIMMUNE, CE*
> B: R/O H PYLORI
> C: R/O EOE
> D-F: R/O CROHN'S, IGG4, AUTOIMMUNE, DY*
>
>
>
> GROSS DESCRIPTION
> A. Received in formalin are multiple pieces of tan, soft tissue aggregating
> to 1.4 x 0.2 x 0.1 cm. Totally submitted in one cassette.
>
> B. Received in formalin is one piece of tan, soft tissue measuring 0.8 x
> 0.2 x 0.1 cm. Totally submitted in one cassette.
>
> C. Received in formalin are multiple pieces of tan, soft tissue aggregating
> to 0.6 x 0.2 x 0.1 cm. Totally submitted in one cassette.
>
> D. Received in formalin is one piece of tan, soft tissue measuring 0.5 x
> 0.4 x 0.1 cm. Totally submitted in one cassette.
>
> E. Received in formalin are multiple pieces of tan, soft tissue aggregating
> to 1.6 x 0.2 x 0.1 cm. Totally submitted in one cassette.
>
> F. Received in formalin are multiple pieces of tan, soft tissue aggregating
> to 0.7 x 0.2 x 0.1 cm. Totally submitted in one cassette.
Original Post
