Headaches and Meds

Probably not, but the only way to know is to stop taking one or both of them and see if your headaches resolve. Just be sure to gradually wean off. I would wean off the lomotil first, since it is a combination of two drugs. It is possible you have become sensitive to the atropine in it. The other drug acts pretty much the same way as the Imodium, through the opioid mu receptors.

Another thought is that you are operating with chronic subclinical dehydration that could be contributing to headaches. Our bodies are not static and our responses change as we age.

Jan

I'd recommend using one or the other, but not both. As Jan wrote, they are acting on the same target, so combining them could be equivalent to an unintentional overdose. And everything else Jan said, too!