Flagyl tolerance?

For years, I was on 500mg of flagyl twice daily (along with my Humira) to help the symptoms of my Crohn's. Each time we tried to taper down, I would see a resurgence in the symptoms (increased frequency, BB, etc) so we kept it as part of my regimen. Eventually, I began to develop numbness in my feet (mainly restricted to my toes), so my GI added 6MP back into the mix, which I had been on years ago, and we tapered down the flagyl until I was off of it completely. Great. Now I have to stop the 6MP for a bit due to complications with anemia and bone marrow, so we restarted the flagyl, but it doesn't feel like it's having any effect this time. Is it possible that after years on it and then stopping it for a few months I could have developed an immunity to its effects?

8/1/1412:48 PM

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Jan DollarModerator, RN, retired

Not you, but perhaps your gut bacteria. You could try tindamax, which is in the same drug class, but it has the same side effects, unfortunately.

Jan

8/1/142:50 PM

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MicheladelfinaTXMember

Thanks, Jan.

8/1/144:49 PM

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