Fecal pills for C-diff--it works !

There was a thread on this topic yesterday.
http://j-pouch.org/eve/forums/...1071921/m/7517019336

I consider it very exciting news, and a better approach than fecal transplant.

Jan

One of the issues for us is that our intestines are structured differently. This approach is essentially a time-released pill, and we know those work unreliably with J-pouches. In a normal gut the colon is a huge target for the transplant/probiotic in capsule form, but much too big for an enema to cover fully. By comparison, a J-pouch is a much smaller but more accessible target. If anyone bothers to study this in J-pouchers, it might turn out that an enema (with the same contents) would work better, since it can hit the target area more reliably. I'm just speculating here...

I am not sure about that Scott. I think that the gel caps release in the small intestine, not necessarily a time release, so should be OK for those without a colon. But, I am sure it is an individual thing.

"To make the pills, researchers processed the feces until it contained only bacteria, and then encapsulated the bacterial concentrate inside three layers of gelatin capsule. This ensured the pills wouldn't leak or disintegrate until they were past the stomach and into the small intestine -- a potential advantage over other methods because it covers more of the GI tract, does not involve invasive and more costly procedures, and is more comfortable for patients, Dr. Louie said."

http://www.sciencedaily.com/re.../10/131004105253.htm

Jan

Fair enough, Jan. As long as it releases in the small bowel, it should work similarly for us, whether we call it "time release" or not.

Yeah, I did have trouble finding an article that was specific enough about the release of the bacteria. Most were article for lay persons and they don't get into details like that, and for us, those details matter!

Jan