ETS2 Gene

@Paul123 posted:

The major breaklthrough discovery that a faulty gene ETS2 gene is 95% responsible for the cause of UC and chrones is outstanding. After living with UC for 45 years and the after effects of surgery  I am extactic the the cause of these horrible conditions is now known.  I always thought is was something to do with the immune systems reaction to bacteria - which seems not far off the mark.

Is anyone yet being treated in tests for the existing meds used for skin cancer that can turn down the faulty  ETS2 gene?

Hi @Paul123, Can you please say more about this and where you found the information? I am curious. I will do a web search myself, too.  Thank you.

Okay, I found a nice summary here by the Crohns and Colitis Canada: https://crohnsandcolitis.ca/Ne...s-Uncovering-the-Hid

It seems that what they discovered is that a gene in the non-coding area of DNA can actually turn on inflammatory action of cells that can lead to IBD and even colorectal cancer. They are not sure how this will translate yet into treatment or prevention, but it is an exciting development. Thank you for making me aware of this, Paul.