Entyvio or any med

I didn't have a stricture but chronic inflammation up into the terminal ileum for many years. Chronic antibiotics cut it down a lot from 2020 on. I also tried several biologicals before, but none of those helped me.

Until I changed to Skyrizi last December, that has a really good effect for me. But everyone is different there, so you will have to try. Anyway I would recommend getting inflammation under control.

You really ought to manage that inflammation, if you can. Diet alone probably won’t be adequate.

I have been dealing with UC since 1972. The concept of “no meds” has been pretty much of a fantasy for me. Maybe some folks can control some symptoms with diet and lifestyle, but my experience is that does not work in the long run. I started out with pancolitis when I was 15 years old and eventually had nearly 2 decades of remission with only an occasional flare and intermittent medication treatment. Then it all blew up and I wound up with a j-pouch. I had another run of some med free years before I was saddled with enteropathic arthritis, then chronic pouchitis. Now I am on Imuran, Inflectra, and sulfasalazine to control my IBD.

The moral of the story is that IBD is random, episodic and not predictable. Personally, I am grateful to be living in a time of so many options!

Jan

i have had a pouch in 2008 with alot of structural issues and then a Remzi redo in 2015. I deal with minor leakage from time to time since my redo which Remzi stated redo with mucousectomy is a 50% chance of having some leakage.

but for the past several years i have had 2 small ulcers in mid pouch that just havent cleared with antibiotics but not really causing any issues. I am still with cleveland clinic and my GI has not talked about biologics at all. I dont want to go on them unless necessary. I would try maybe Budesonide before trying biologics but i dont have any stricture issues so you are a little different.