Well, this is a tough one. As you probably have noticed advice and experience varies widely. One person’s experience does not predict another’s. The advice can be helpful or not.
That said, my take on the whole biologic issue has been that they are worth trying and the trend now is to use them earlier with IBD in general to avoid surgery when possible because they are that safe and effective. Most of the adverse effects are reversible when discontinued, and the lymphoma risk is quite slight (remember, you can get lymphoma or any other cancer without taking biologics).
After many, many years of biologics, I am happy to report that I personally have not suffered any adverse effects. I have been on Enbrel, Humira, Simponi, Cimzia, and Remicade. All were for enteropathic arthritis, but my GI recommended Remicade once I developed chronic pouchitis. Specifically, he wanted me to not take antibiotics on a chronic basis, as they have their own risk profile. I was doing OK on antibiotics, but was willing to change. Entyvio is the only one I have not tried. It was going to be next if Remicade failed.
I have had numerous vaccines while on biologics, and specifically Remicade. I had my first Covid vaccine 2 weeks ago. No problems. I had surgery to remove my adrenal gland and cardiac ablation while on biologics. I have other comorbidities, like diabetes, mild chronic kidney disease, cardiac arrhythmias and enteropathic arthritis, but that does not stop me from treating my pouchitis.
My best advice is to figure out which risks you are willing to live with. Try not to be so fearful of potential side effects that you are unable to fully consider your options. Plus, it is OK to decide to go with an option now and change your mind later. But, just know, that with Remicade, once you start it you generally cannot resume it after you have stopped it for a prolonged period. That is when antibodies tend to form against it.
I hope you figure out what your best path to wellness is soon. Good luck!
Jan 
