I saw my Gastro Specialist today and he prescribed a low dose of dothiepin for my ongoing irritable bowel symptoms which I've had ever since my last bout of pouchitis. Just after views/opinions re this. Thanks
Dothiepin is a tricyclic antidepressant, similar to amitriptyline which is commonly used in the US for IBS/IPS. It can reduce your awareness of gut sensations so you perceive less pain. It works very well for some. You just need to be alert for side effects with long term use.
Thanks for the reply. I have been on colese with little effect so he wants to give this a go. I am super reluctant due to potential side effects but he assures me 25mg is a small dose. Guess I.ll see how I go :/
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