The NSAIDs can cause J-pouchers trouble, but it's probably not a big deal with occasional use. Are you planning to take it every day, or less often ("as needed")?

The only NSAID I can take is Celebrex (because of allergies), but I only take it about 4 times per week.

I think this is one of those cases of "things change." Now that you have arthritis to treat, you have more than just your pouch to deal with. Maybe you will tolerate NSAIDs, maybe not. Unless you have had past experience with intolerable GI side effects, you just cannot know if it will be an issue for you.

Yes, they will increase your risk for pouchitis, GI bleeding, liver inflammation, heart irritation, and more. But, you also need to be able to function and live your life. I was able to tolerate high dose NSAIDs for years before I had to stop them due to liver inflammation and pouchitis. By then, other treatments became available to me and I switched to them.

So, for me, it was worth it to take them, even knowing it might not be for very long. I still take ibuprofen or Relafen when I have a flare, but I limit it to two weeks now.

Jan

I have periodic back pain. When this happens, I take diclofenac. I try to get off it as soon as possible, but sometimes have to take it twice a day for a month or longer. My surgeon said not to worry, but to keep an eye out for bleeding. So far, no problems. I pray that continues as this is really the only thing I found that works well when the pain gets unbearable.