Hydrocortisone or mesalamine suppositories. Neither of those have sulfa.

The only UC med with sulfa is sulfasalazine, and that is oral.

Jan

Thanks Jan...I'm currently on cort enemas...have a scope tomorrow...in 22 years I've never had this problem...I'm actually just assuming its the cuffitis but I seem to have the symptoms...if I do have it, is it easily treated or is this a sign of more issues to come...I have Crohns as well now and im treated with cimzia...remicade worked great for both the crohns and pouchitis but I had a reaction to it and after almost 5 years I built up antibodies against humira...cimzia helps the crohns but does nothing for my pouchitis..

If the cimzia is not helping the pouchitis, have you treated with antibiotics? I would presume you had, since it is ptretty standard. What about using methotrexate in combination with the cimzia? I use Simponi, but that has not been approved for Crohn's, at leadt not yet.

Cuffitis may or may not be chronic, and if you have an anal stricture and/or chronic poucitis, that can worsen things. You can have bleeding with pouchitis too, just less likely.

I am sure that you know that pouch failure is more likely with Crohn's... But, I understand wanting to avoid pouch removal if you can, especially since it will not cure the Crohn's. Good luck!

Jan

I use cipro and flagyl for the pouchitis...they work it's just that it was great not having to take them with the remicade...I know the risk of pouch failure with Crohns...all to aware and I'm not going to lose it without a fight...I've had a stricture at the anastomoses for over 10 years and it's never bothered me...I've actually never had problems going until now...and I've never had bleeding with my jpouch until now...the symptoms appear to be cuffitis but who knows...does methotrexate help with pouchitis?...I have psoriasis as well which would actually help me get on Simponi or stelara if needed...I'm also glad to hear that entyvio will be approved soon for both Crohns and UC...