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4 replies

Cipro and Flagyl

C Chris_JPouchMember
Hi,

I had my takedown 5 months ago and haven't been doing the best. My dog put me on a course of Cipro and Flagyl which I was great on. As soon as I went off the symptoms came back in terms of increased formation and loose movements. Doc put me on a second time and I again did well but then struggled when I went off. I went for a scope and everything looked fine. They put me on the antibiotics for a third time and I started off doing well. I'm taking 1 pill of each a day still but am starting to get worse. Is it possible I'm building up a resistance to these meds. If I don't have pouchitis what are these meds curing?

What should I do?

Thanks,

Chris
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J jeaneMember
You could have small bowel bacteria overgrowth. I had my takedown over two years ago and I am pretty much on continual antibiotics. I don't really have pouchitis but I suffered greatly with anal issues like severe burning, difficulty emptying my pouch and often anal bleeding when not taking antibiotics. I would think you have not been on them long enough fir the meds to no longer be working. You may want to talk to your doctor about trying a different antibiotic.
Scott FScott FMember
You have a few options. You may choose (or need) to stay on antibiotics. Some folks stay on one for quite a while, others rotate them every few weeks. Since yours seems to be losing its effectiveness, rotating would be a good idea. You may want to add a substantial probiotic, like VSL #3 DS, which seems to keep pouchitis at bay for some of us. And you should at least try substantially reducing carbs for a while. It's a big change, but it might also have a big impact.
CTBarristerCTBarristerMember
I have rotated antibiotics for 18 years. I tolerate all of the antibiotics well and if you rotate 3 or 4 antibiotics aggressively every week or two, no resistance will build up. You have to be cognizant of what the antibiotic families are and when you rotate antibiotics, do not use two in sequence that are in the same family. For example, you do not rotate from cipro to levacquin as they are in the same family which is called fluoroquinolone. Rotating directly from one antibiotic family member to the other is committing antibiotic incest.

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