I only use them for cuffitis, and just during a flare. I take sulfasalazine for maintenance.
You only use them once a day now that they are double dose (1000mg). When they were 500mg you could do 1-2 times a day. But, I have no doubt that some docs prescribe the 1000mg suppositories twice a day.
Basically, it is one of those "whatever works for you" scenarios. You can use them for maintenance or to treat a flare. My GI told me that once in remission I could taper off to whatever frequency that kept me stable. I opted for the oral route instead for the maintenance, mostly for convenience sake.
Jan