I had of lot of mucus between steps, but it didn't cause me any discomfort. Assuming you have a loop ileo, some stool/digestive enzymes can pass through the pouch, which might be causing your problem, as the enzymes are quite acidic and can be very caustic on skin. In addition to keeping the area clean and dry, you can try a zinc-based ointment such as Calmoseptine; you can actually put some up right inside the anus (I hope you're not squeemish). Alternatively, if the area is constantly moist then you might also have an yeast infection going on. You can try an over the counter antifungal cream such as Canestan (available in the feminine hygiene aisle). Finally, after you apply any cream, dust the whole area with baby powder. This not only helps to keep things dry, but helps set the ointment in place and prevent it from transferring onto your clothing.