Bactrim usually works very well for me, but I take double strength twice a day. Maybe single strength will work for you.

Cipro gives me horrendous joint and tendon pain, and Flagyl gives me nausea and vomiting, so Bactrim is my standard go-to antibiotic.

What does your doctor say?

That is interesting, first time heard of using bactrim to fight pouchitis.
May be some time I'll give it a try.

Another unusual antibiotic my doc used. One is Doxycycline : did not work . Second is Moxifloxacin : a rather new drug gave me moderate result.