Alicaforsen; new drug for chronic pouchitis

Rick DeutschMember

I just came across information about a new drug to treat chronic pouchitis that is apparently showing promising results in trials. Wondering whether anyone else on this forum can share info about this. By the way, Dr. Shen is a member of the U.S. board of advisors for the UK-based pharma company that hopes to bring this drug to market. A detailed PDF is at:http://onlinelibrary.wiley.com/store/10.1111/j.1365-2036.2004.01863.x/asset/j.1365-2036.2004.01863.x.pdf?v=1&t=hox6irs6&s=20901ecd508ace576b7a53c370e77ca79e09bbb7

12/7/131:22 PM

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CTBarristerMember

quote:
http://onlinelibrary.wiley.com/store/10.1111/j.1365-2036.2004.01863.x/asset/j.1365-2036.2004.01863.x.pdf?v=1&t=hox6irs6&s=20901ecd508ace576b7a53c370e77ca79e09bbb7

This link does not appear to be working for me. I did read some information suggesting this drug is made in an enema format and has been successful treating pouchitis in trials. The mechanism of action is described as inhibiting white blood cell adherence, migration and activation - basically a switching off of the inflammatory process enabling tissue healing.

12/7/133:55 PM

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