I agree that a thorough site search will provide the best advice. Personally, I had a great hospital stay; I was discharged 24 hours after surgery. Once I got home, the butt burn started and it is HORRIBLE. I am still experiencing it 7 weeks post-takedown. I use Desitin after I go, but it was suggested by someone on here to apply it before I go also, as a protective barrier. I have worn Depends every night since my takedown, but have only actually needed them once for nighttime leakage. They are more of a comfort for me, just knowing that it would be okay to have an accident during the night (never thought I would say this as a 26-year-old). I also take Questran before eating, though I could be stricter about using it every time I eat. It seems to help with butt burn because it reduces the bile in your gut (or at least that's what I think it does...).
Good luck, and please do search the rest of the site -- this community is very helpful and supportive and they provide great advice!