I have had these sorts of random pimple lesions. One time it was inside my nose and wound up being a major abscess that went into my lip. I have also had leg lesions that seemed like erythema nodosum associated with chills and fever. But it all seems so random. It has been treated on a case by case basis for me. I never was advised to stop my biologic except for the one time I was on antibiotics when my infusion was scheduled. In that case, it was just a one week delay. I suppose it could all be related, but since my pouchitis is so well controlled, I am sticking with the Inflectra (Remicade biosimilar).
If you find out anything, I would love to hear it!
Jan