Joint pain is on the list of potential side effects, but fever isn’t specifically mentioned. If it’s happened every time it seems unreasonable to presume that it isn’t related. If it isn’t getting worse each time, as a delayed “allergic” reaction might, then you get to ask yourself if the discomfort is worth the benefit. There are other biologic options available, but with no guarantees they’ll work as well or have a better set of side effects.

On the Stellara website they do mention both joint pain and fever as a side effect, along with a long list of others. Do you take premeds before your treatment? Perhaps taking some Tylenol and an antihistamine before your injection may help (if you don’t already do this). Since your reaction symptoms are a little delayed, perhaps they are less of a concern. But, they definitely seem related to me.

But, like Scott said, it is up to you whether it is a reasonable trade off.

Jan

Thank you both for replying. I did not take premeds before treatment but have decided to discontinue stelara due to this immune response. It did work wonderfully for the first 6months though. Back to cipro Flagyl sulfasalazine cocktails 🍸.