Although my surgeon is dead set against radiation should I ever get a diagnosis of PC, someone posted here a while back that they had successfully undergone radiation with a jpouch.

A product call SPACE OAR, which is a hydro-gel was injected btw the prostate and jpouch to shield the the pouch from the radiation.

if you do a search, you should find the thread.

A friend of mine is doing well with Pluvicto, and that might target the radiation well enough to the cellular level to protect the pouch and the rest of the gut. He does have to isolate for a few days after each infusion.