In my personal opinion, I think the liquid works better. I think the enema covers more area than the suppositories.

It should work just as well if you can retain it for an extended period. If you have to squirt it back out then I wouldn’t expect good results.

Yes, I can keep it for 4 hours for sure.

Yes. I can confirm that the enemas work just as good or better than the suppositories!

Thanks for the review. Is enema only used for cuffitis or can it also be used for pouchitis? I have had a J pouch for 5 years and have never had an endoscopy. It would probably be a good idea to do that

Enterin- I had very little luck using these enemas to treat active pouchitis. If you have moderate or worse pouchitis it's typically very difficult to retain the enemas for any significant period of time. As Scott mentioned, the therapeutic benefit likely corresponds to the user's ability to retain the enema and not have an immediate and irresistible urge to squirt right back out.

I’ve only taken it for my cuffitis, and prior to jpouch I took it for proctitis. I have never heard it taken for pouchititis.

if you are taking or considering taking this medication, the prescribing doctor I assume would be doing so for a reason and an endoscopy would be warranted.

I don’t know how hard it is to find a J-pouch-knowledgeable gastroenterologist in Croatia, but it’s worth getting started on that if the diagnosis is uncertain. As others wrote, mesalamine isn’t a good choice to treat pouchitis.

You can find excellent doctors here. How long is the expected treatment of cuffitis with an enema?

Hard to say.

since my reason for the colectomy was high grade dysplasia in the rectum, my GI and I have decided to treat my cuffitis aggressively. I have been on mesalamine  for over a year and at least until my next scope.

you definitely want this managed by a “knowledgeable” GI.

Cuffitis behaves a lot like UC. It can wax and wane on its own, it can be chronically troublesome, and it can disappear for a long time. Mesalamine isn't generally a short-term treatment that makes cuffitis go away. It's usually a long-term treatment to keep cuffitis under (hopefully) good control. Bad cuffitis can be definitively treated with pouch advancement surgery, but that is generally reserved for when medication isn't working adequately.