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With a j-pouch, you lose more water through BMs and our transit time and absorption is different to the standard population.

So the volume of urine we pass in 24 hours is probably going to be lower.

But what about the composition?

I don’t have a GI specialist or surgeon at the moment to ask, and my current GP doesn’t know the answer. Specialist who ordered tests hadn’t heard of the j-pouch, so he’s definitely not going to know!

The two tests I had were 24-hour sodium, and 24-hour catecholamines and metanephrines.

I don’t think the catecholamines and metanephrines would be affected because they come from the blood.

But I suspect the sodium could be affected because we might lose a bit more sodium via BMs.

Does anyone know? Or can you point me to a reference?

I don’t want to have unnecessary testing and investigations because people can’t allow for the effect of a j-pouch when interpreting results.

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@Scott F posted:

I think a properly hydrated J-poucher should have perfectly normal urine lab results. It’s true that it’s easier for a J-poucher to become dehydrated or to lose electrolytes, but these conditions will do just as much damage to a J-poucher as anyone else, and we need to prevent them.

Thanks, Scott.

I just realised that the doctor prescribed a medication at the same time that causes diarrhoea, so now I don’t know what to think. Even in a “normal” person, it seems like this medication side effect could disrupt a sodium urine test.

Would the electrolytes lost due to diarrhoea, including sodium, be through the bowel?

(That’s probably obvious, but I’m feeling a bit brain fogged at the moment.)

K

I prefer to avoid the word “diarrhea” for J-pouchers, because I think it’s ambiguous, ranging from perfectly appropriate soft stools to catastrophic fluid loss. In any case, the “normal” way diarrhea lowers electrolytes in folks with colons is by running fluid too rapidly past a very large membrane (the colon). This won’t work exactly the same with a J-pouch, but the key factors (liquid stool and rapid transit time) will still operate to some degree.

The simple point is that we need to stay hydrated, and when things get rough we may need to replace electrolytes.

Scott F

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