I use the *very* similar VSL #3. The dose matters a lot, and it’s so expensive that many people take too small a dose. I take four double-strength packets (900 billion CFU each) per day, split between morning and dinner time. At that dose there seems to be an appreciable effect for me.

Hi Scott

I also take a high dose of Vivomixx every day for some time now. Have you heard about the possibility of developing SIBO from taking a high dose of probiotics for a long time? I ve read from another patient who claims to have developed SIBO from high dose of Vivomixx (I think 2 sachets of the 450bln strength) taken for a long time, and I ve also read that Dr Shen advises that probiotics are good for the long intestine and I havent read from any of his patients that he advises on taking a high dose of probiotics for long term.

I am wondering what is your knowledge on this?

thanks!

I have read the claims of an association between probiotics and SIBO, but on balance I think they are likely to be incorrect. There’s certainly no published evidence of this that I’m aware of. I’ve also heard that Dr. Shen doesn’t put much stock in probiotics, but I’ve also read the articles that show some benefit, and (as best as I can assess) found some benefit for myself. I’m not sure why he came to his conclusion, but if I ever see him I hope to discuss it with him. His ideas are likely more nuanced than get reported here.

Thank you for the reply Scott. Would also like to understand more about this.