Is it possible you have an anal fissure? I have not experienced this but I have seen people say they feel like razor blades coming out. I’m sorry you are in so much pain!

If you’re in that much pain internally then you need to get your painful butt to the ER for a scope or CT.  If you have some kind of internal tear then you are courting sepsis.

Thanks for your reply. I had scope of my pouch yesterday. I am swollen and inflamed throughout and am being sent to GI for biologic discussion or have a permanent ileostomy which I am okay with. I worked for a rheumatologist for years with many patients with autoimmune diseases being on a variety of biologics.  I saw too often the down side of severe side effects and am hesitant. I also know many with a Jpouch who did not respond well to biologics with regards improvement of symptoms. My incontinence is getting the better of me mentally and my social life and sports suffer greatly. I have 3 BMs every single overnight; and I mean full BMs, not a little leakage. Anyways, just tired.

I hope doc did not miss a leakage  I have no fever, just very crampy. For now, I will just continue with Flagyl as it is all I've got. I will go to emergency if this G's escalate.

Ilex cream does help the skin irritation.  Maybe that will give you some relief.

I wish you the best!  Sounds awful.  I’m on Entyvio and it’s working great for me.  

Minimal side effects on Entyvio up for you?  How long have you been on it?

About 3 years now and I frankly can’t tell that I’m taking it as far as side effects.  So, none.  It’s controlling chronic pouchitis.  I did Humira for several years prior, which was easier as it’s an at home simple injection, but it stopped working after many years.  Entyvio is infusion, so it’s a little more of a hassle.  Although I just saw that there’s a company now that will come to your home and do infusions right there.