@RondaC, CBD will not treat pouchitis. It’s no substitute for Cipro, flagyl, or biologics. However, I have found CBD very helpful for the insomnia that has long plagued me and it also relaxes me with no sedative effects. So while it won’t treat pouchitis, it can have other beneficial effects—at least that’s been my experience. (I’m fortunate enough to live in a state where medical cannabis and related products can be purchased legally.) Check with your medical care providers, but mine are fine with this. Good luck!