Where are you thinking of putting the ozone? It’s fairly toxic stuff. I’d suggest getting a proper diagnosis so you don’t have to call it a “flare up” any more.

Thanks for response, rectal injection is the treatment i'm refering to. Cipro, Flagyl does not seem to help. Only thing that has help has been Humira. But almost died with infection after i had a kidney removed because of cancer. I blame the Humira so don't take anymore.

By the way, i also had my operation done 2002, always dealing with Chronic Pouchitis.

Untreated chronic pouchitis is pretty awful. I don’t know if you have a creative gastroenterologist, but there may be reasonable things you haven’t tried that are wiser than ozone. Possibilities include combination antibiotics (e.g. Cipro + Flagyl), other antibiotics (e.g. rifaximin, Tindamax, Augmentin), a biologic that you stop before having any future surgery, etc. Good luck!

Thanks Scott for info, will look into some of the drugs you mention