The loss of ones colon does not significantly alter the immune response. The presence of an inflammatory disease can have a larger effect, though, even without a colon.

The story is more complicated than a “strong” or “weakened” immune system. For one thing, the immune system is a bunch of separate systems working together. For another, the worst consequences of some infections (like Coronavirus) seem to be from an overly aggressive immune response, rather than from a failure to recognize and fight the infection. 

I’m not aware of any data about the effect of underlying IBD on Coronavirus.

So would you say that if we are having active  that our immune response would be on overdrive and would make the coronavirus more dangerous for us?

No one knows, unfortunately. Just because the immune system is getting over-excited about your rectal cuff mucosa doesn’t mean it will freak out about what looks to it like a cold virus. I’m planning to try like heck not to catch this thing.

Scott, thank you so much! I will take the normal precautions and not act like a special case. 

When I was operated on 1986 I was told not to travel to 'dirty' countries because I am more susceptible to catching things now that my colon was removed. And that is all I was ever told. And back then I was so young I never thought to ask any questions about that but now I know what the surgeon was referring to.

I think I heard something like that, as well. And that's why I've always thought I had to be extra careful. So we think they meant more susceptible to catching stomach bugs? Personally, if I hear of someone having one of those, I run for the hills!

 Well when I have a cold or sinus issues including a cough it doesn’t settle well with my jpouch.  All that drains right down my throat and starts all my problems.  We all are  slightly dehydrated.  So I am concerned.  I’m just making sure that I’m aware of my surroundings.