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I was on a maintenance routine with Cipro that was working great for months. Then last week I got the virus that's been going around and it wreaked havoc on my pouch. Now I've got a major flare up. I started flagyl last week but not much luck. Now I'm doing the combo strategy of both Cipro and Flagyl. IF these two don't do the trick, what next? They've always worked in the past.

 

This is the SECOND time in the past three years that a virus induced pouchitis. Same thing happened about two years ago. Anyone else experience similar issues?

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You’re not alone in experiencing an extended recovery from an “ordinary” GI bug. I’m not sure it’s pouchitis, though, or at least not the usual kind. I’ve had the same experience, even though I’m always on Cipro and Flagyl, and eventually things seem to settle down on their own. If/when my Cipro and Flagyl *really* stop working permanently I expect the next step to be one of the biologic medications, perhaps Humira or Entyvio. A number of folks here have successfully made that transition, some with a biologic alone and some with combination therapies.

Scott F

Everyone is a bit different, so it’s hard to tell except retrospectively. Since we don’t really know what causes occasional bouts of “normal” pouchitis, it’s reasonable to imagine that some GI disruptions could lead to it. If it clears up on its own then it’s probably not “normal” pouchitis, just a slow recovery from the GI bug. People vary in how willing they are to try a course of antibiotics, and how willing they are to put up with the symptoms without taking action - personal preference matters here.

Scott F

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