Hey all

I've had a issues with what I suspected was pouchitis for a long time. It turned out to be a reaction to Naproxen and other NSAID's which I used to treat back pain.

As it turned out the back pain was from an inflammation in the sacroiliac joints - which happens to be associated UC/Crohn's. Because of my bad reaction to NSAID's I would start taking Humira twice a month. It worked wonders for my back pain which at that point had gotten very bad gradually. I was in constant discomfort or flat out pain but Humira fixed me up pretty much over night.

However... after taking two shots I've realized that Humira causes diarrhea. And bad. After the first shot I got diarrhea immediately. At first I suspected it was my J pouch acting up as it does often for different reasons. But the diarrhea was persistent and gradually disappeared right about when it was time to take another shot of Humira. Second shot, boom, diarrhea for a week and counting.

I'm sure that there are other people out there who have been diagnosed with inflammation in joints and treated with Humira. Do you have any advice for me?

I know I'm not supposed to but I tried antibiotics while on Humira (Cipro and Xifaxan) to rule out pouchitis but it hasn't worked. 

Should I be worried?

Will I have to give up this miracle drug?

Will my body adjust, will the diarrhea go away?

Are there any other Good treatment alternatives if Humira is a no go?

Thanks everyone!