My surgeon has me taking Align for now. I am also new, 10 mos. out. I can't really say how well it's working, but I have had minimal issues with my pouch so far. I guess the real test will be if I eventually develop pouchitis. I don't dwell on that idea and am just doing the best I can for my pouch. If you belong to Costco, Align will cost about 54.00 for 12 weeks when it is not on sale. I stock up when it is on sale for about 10.00 cheaper. I did check the price on VSL -3 and VSL-3ds. Also, if your doctor does prescribe VSL-3 ds, you can go to their website to look for financial assistance. My sister currently gets it for free based on financial need. Doesn't hurt to take a look. I don't qualify now, but that may change in 6 mos. when I retire. Hope this helps.