Right after my original surgery I was diagnosed with chronic pouchitis and took cipro and flagyl daily for maintenance, which worked really well for years. When I became resistant to these drugs I was at a loss and spent another two years going from doctor to doctor trying to figure out what was going on. It got so bad that I started flying from the East Coast to see Dr. Shen at the Cleveland Clinic. I tested positive for c diff and did amazingly well on vancomycin but have gotten worse since coming off of it. This leads me to believe that for all these years I was misdiagnosed with pouchitis when I actually had c diff and I can't believe I had not been tested for it all these years. The Flagyl I was taking for the pouchitis would have treated it c diff, while the cipro would have ensured that I got it again every time I tried to stop taking the antibiotics.
Anyway, after two weeks of taking vancomycin in which I felt better than I have felt in a long time, my symptoms have returned and Dr. Shen says I should do a fecal transplant rather than another course of antibiotics. Has anyone had a fecal transplant to treat c diff in their pouch?