I have been given bottles of opium tincture far too generously by my careless surgeon. I live in an opioid epidemic state. My surgeon told me I'd be on it for life so I just gave up and started taking more. I have an Excellent GI who told me no surgeon should ever have told me about it and he helped me wean with a small daily dose of methadone (5mg).
It has been working perfectly, it also has a lot of off-label uses.
methadone is also excellent for shutting down bowels LONG TERM, while the tincture was short term, making me need more- growing into addiction. I very much recommend methadone for weaning off opium. Also, VIBERZI is great for diareah. It's new.