Years before having my colon removed I got c.diff from taking Cipro for sinus infections. I wish I could have taken it for my pouchitis.
I took a lot of flagyl for pouchitis until I it was making my peripheral neuropathy, in my feet, worse.
I was alternating augmenten and xifaxan before I had surgery diverting to a permanent ileostomy. The latter is very expensive but is specific for intestines. (There's a TV commercial out marketing it for IBS with diarrhea. It includes a pink cartoon glob of intestines.)
I'm not suggesting people don't take these. Just a warning. I had c.diff in my pouch. Many courses of flagyl eventually got rid of it.