Scott thanks for sharing your story. My cipro and flagyl stopped working and my Dr gave up on me. So I tried Scott's plan and am on 1 500mg of cipro and 1 250mg of flagyl a day. It is helping me and I'm don't have no side effects. Not to have butt pain is the best. I also take pepmo sometimes because I can't stay away from chocolate. So things could be better if I could stay away from sweets.lol I also am using the canasa supositories maybe five days a week. I know I will have to find another dr once my scripts run out, but for now I'm good. I just take day by day. Ny stress is less also since I started raising Monarch butterflies again, very relaxing and rewarding.