I had my third surgery April 2012. Aftet all that and I'm still suffering. First it was pouchitis. We got that under control and now the cuffitis is brutal. The few inches of large intestine left is severely inflamed. I've tried Canasa suppositories, cortifoam, steroids, antibiotics, and Humira with little relief. About to start simponi. Any one out there have any other ideas? Slipping into desperation.