It's been a year since my J Pouch was constructed and due to fistula tests and repair it will be awhile yet until the illeostomy is closed. I've dealt with many instances of leakage from the seal breaking but lately I've noticed another pattern and I was wondering if anyone has experienced the same. When I take morphine for pain...(only 1 mg) I've found that it is just a matter of hours later that my seal is blown. What is the correlation?