Could SIBO make your calprotectin level go up? My son's level jumped almost 200 points in 2 weeks. If it is not SIBO, I guess it would be cuffitis or pouchitis?
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Two studies of the connection found there was no relationship between FC levels and SIBO:
CONCLUSIONS:
FC values are negative in children affected by SIBO, not differing from those obtained in healthy children, suggesting that no subclinical intestinal inflammation involving neutrophils occurs in patients with higher proliferation of bacteria in the small bowel. The presence of high FC levels in children affected by SIBO might not be caused by bacterial overgrowth itself and, in this case, another cause should be investigated.
http://www.ncbi.nlm.nih.gov/pubmed/22195368 (2011)
http://www.ncbi.nlm.nih.gov/pubmed/18431069 (2008)
CONCLUSIONS:
FC values are negative in children affected by SIBO, not differing from those obtained in healthy children, suggesting that no subclinical intestinal inflammation involving neutrophils occurs in patients with higher proliferation of bacteria in the small bowel. The presence of high FC levels in children affected by SIBO might not be caused by bacterial overgrowth itself and, in this case, another cause should be investigated.
http://www.ncbi.nlm.nih.gov/pubmed/22195368 (2011)
http://www.ncbi.nlm.nih.gov/pubmed/18431069 (2008)
And for your other question, there is a positive relationship between high FC levels and inflammation - so pouchitis or cuffitis is a good guess.
Steve
Steve
Thank you ElmerFudd/Steve. I appreciate that info.