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Cipro is generally discouraged during pregnancy as it is a Class C drug and they really have no data on it's impact during pregnancy. Flagyl is usually considered ok, preferably after 1st trimester, but I think some folks here took it throughout. As with any meds, the health of the mother is weighed against the potential impact to the baby.

I would recommend managing your pouchitis with the least problematic meds possible, even now, so that during pregnancy you don't have to suddenly switch.
J
I managed really well with chronic pouchitis. I was using Cipro mainly prior to getting pregnant. I switched to Augmentin (probably your best bet for a safe and effective antibiotic you can take throughout), got pregnant, and took a low dose my entire pregnancy and 6 months of nursing. it basically stopped working for me at that point. i used flagyl once during the pregnancy toward the end, but it never really worked well for me. it is considered safe in the 2nd and 3rd trimesters as jill said. there really aren't too many options for antibiotics that treat pouchitis and that are considered safe so you won't be able to much of a rotation. fortunately for many on the boards...seems like most can go a pretty long time on augmentin before it stops working.
clz81

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